C.-Y. Huang

Reconstructing fresh green leaf spectra in the SWIR-2 region (2001-2500 nm) collected in a humid environment by referring to publicly available green leaf spectral databases

This paper proposes a statistical method to reconstruct noise-free SWIR-2 leaf spectra using reference databases, achieving low RMSE in reflectance and transmittance.

Functional divergence shaped the network architecture of plant immune receptors

The paper shows how functional divergence in NRC3 variants shapes the genetic architecture of the NLR network in solanaceous plants, leading to subfunctionalization and increased immune system complexity.

Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

This study identifies 29 fragment hits against SARS-CoV-2 main protease using X-ray crystallography, including two covalent binders, and shows crystal form affects fragment binding poses.

NRC immune receptor networks show diversified hierarchical genetic architecture across plant lineages

The paper investigates the evolution of NRC immune receptor networks across plant lineages, finding significant expansion and complexity in lamiids compared to Ericales and campanulids.

Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation

This study identifies RAP2 GTPase as a central integrator of cytoskeletal signals in Hippo pathway regulation, showing its role in mediating responses to cytoskeletal changes and its impact on Hippo kinase activity.

Dearth of smoking-induced mutations in NSRO-driven non-small-cell lung cancer despite smoking exposure

The paper examines genomic and transcriptomic changes in NSRO-driven NSCLCs in smokers and non-smokers, finding no smoking-induced mutations but higher transcriptomic cell cycle activity in smokers.

Hippo Signaling Modulates Mechano-inflammatory Responses of Chondrocytes

This study shows that Hippo signaling modulates chondrocyte responses to mechanical overload by regulating NF-kappaB-mediated inflammation and matrix degradation.

Ovulation sources coagulation protease cascade and hepatocyte growth factor to support physiological growth and malignant transformation

This paper identifies the coagulation protease cascade and hepatocyte growth factor (HGF) as mediators of sustained transformation activity from ovulation, promoting both physiological repair and malignant transformation of ovarian tissues.

The Crystal Structure of Bromide-bound GtACR1 Reveals a Pre-Activated State in the Transmembrane Anion Tunnel

The paper reports the crystal structure of bromide-bound GtACR1, showing structural changes that relax constrictions in the anion tunnel, indicating a transition to a pre-activated state.

An allometric scaling approach to estimate epiphytic bryophyte biomass in tropical montane cloud forests

This paper develops an allometric scaling method to estimate epiphytic bryophyte biomass in tropical montane cloud forests using field measurements and interpolation.

Long-Term Outcomes of Pediatric Graves Disease Patients Treated with Anti-Thyroid Drugs: Experience from a Taiwan Medical Center

This study examines long-term outcomes of pediatric Graves disease patients treated with anti-thyroid drugs, finding that younger age, no family history of thyroid disease, and lower TRAb levels are associated with remission.

Crystal Structure of a Natural Light-Gated Anion Channelrhodopsin

This paper presents the X-ray structure of GtACR1, revealing a novel mechanism for anion conductance involving the Schiff base and tunnel architecture.

Response to Qian et al (2017): Daily and seasonal climate variations are both critical in the evolution of species’ elevational range size

The paper addresses criticisms of their previous study on climate variability's impact on species' elevational range size by clarifying their use of structural equation modeling and reiterating their findings using multiple statistical methods.