Molecular BiologyNature Cell BiologyPeer-reviewed
Redox Regulation of m6A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes
Dario F. De Jesus, Zijie Scott Zhang, Natalie K. Brown…·Rohit Kulkarni
This study shows that m6A methylation, regulated by METTL3, controls the innate immune response in β-cells during T1D onset by modulating OAS mRNA stability.