Cancer BiologyJournal of Clinical InvestigationPeer-reviewed
IL-7-mediated expansion of autologous lymphocytes increases CD8+ VLA-4 expression and accumulation in glioblastoma models
Kirit Singh, Kelly M. Hotchkiss, Sarah L. Cook…·Peter Edward Fecci
This study shows that IL-7-expanded autologous lymphocytes increase VLA-4 expression and accumulate in glioblastoma tumors, enhancing the effectiveness of T cell-based therapies.