Author

Gavin E. Shavey

University of California, San Francisco

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

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Andrew H. NgiD· 1 shared Hana El‐SamadiD· 1 shared Hersh K. BhargavaiD· 1 shared Matthew S. KimiD· 1 shared Wendell A. LimiD· 1 shared

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Andrew H. NgORCID

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Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedJul 11, 2024

Degron-based bioPROTACs for controlling signaling in CAR T cells

Matthew S. Kim, Hersh K. Bhargava, Gavin E. Shavey…·Andrew H. Ng

This paper introduces bioPROTACs, a genetic tool to control CAR T cell signaling by degrading specific proteins, demonstrating its effectiveness in inhibiting CAR signaling in human T cells.

26 citations

humanexperimental assay

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