NeuroscienceeNeuroPeer-reviewed
Dopamine receptor 1 specific CRISPRa mice exhibit disrupted behaviors and striatal baseline cellular activity
Rianne R. Campbell, Mikah Green, Eric Y. Choi…·Mary Kay Lobo
This paper shows that CRISPR-dCas9 systems can cause behavioral and cellular changes in mice even without targeting specific genes, highlighting the need for validation.
2 citations