Late mitochondrial origin is pure artefact
William F Martin, Mayo Roettger, Chuan Ku…·Giddy Landan
The paper refutes a claim about a late mitochondrial origin by identifying statistical and interpretive flaws in the original study.
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5 papers
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William F Martin, Mayo Roettger, Chuan Ku…·Giddy Landan
The paper refutes a claim about a late mitochondrial origin by identifying statistical and interpretive flaws in the original study.
Kiyoshi Ezawa, Dan Graur, Giddy Landan
This paper develops a theoretical framework for calculating sequence alignment probabilities under a general continuous-time Markov model of insertions and deletions using perturbation theory.
Kiyoshi Ezawa, Dan Graur, Giddy Landan
The paper develops an algorithm to approximate the probability of local multiple sequence alignments using a perturbative formulation of a continuous-time Markov model of indels, showing it works well for moderate gap and branch lengths.
Kiyoshi Ezawa, Dan Graur, Giddy Landan
This paper applies an ab initio perturbative formulation to calculate alignment probabilities under indel models, showing that fewest-indel terms can accurately approximate local alignment probabilities under modest conditions.
Kiyoshi Ezawa, Dan Graur, Giddy Landan
This paper extends a perturbative formulation of a continuous-time Markov model of sequence evolution to include substitutions and other mutations like genomic rearrangements.