NeuroscienceBrainPeer-reviewed
Proteostasis as a fundamental principle of Tau immunotherapy
Esteban Cruz, Rebecca M. Nisbet, Pranesh Padmanabhan…·Jürgen Götz
This study shows that a novel Tau antibody, RNJ1, restores proteostasis in a tauopathy model by reducing pathological Tau and normalizing protein and phosphoprotein levels.
14 citations