GenomicsGenome ResearchPeer-reviewed
Ultra-low input single tube linked-read library method enables short-read NGS systems to generate highly accurate and economical long-range sequencing information for de novo genome assembly and haplotype phasing
Zhoutao Chen, Long Pham, Tsai-Chin Wu…·Ming Lei
The paper introduces a low-cost, high-accuracy method for generating long-range sequencing data using short-read NGS systems, enabling de novo genome assembly and haplotype phasing with minimal DNA input.
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