Molecular BiologyScientific ReportsPeer-reviewed
Noncannonical functions of Ku may underlie essentiality in human cells
Rachel D. Kelly, Gursimran Parmar, Laila Bayat…·Caroline Schild‐Poulter
This study establishes a conditional Ku70 knockout system in human cells to investigate the causes of Ku essentiality, finding that loss of Ku affects multiple cellular processes beyond DNA repair and telomere maintenance.
9 citations