NeurosciencebioRxivPreprint
Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation
Philipp Hornauer, Gustavo Prack, Nadia Anastasi…·Manuel S. Schröter
The paper introduces DeePhys, a tool for functional phenotyping of neurons using electrophysiological data, and shows it can predict genotype and age in iPSC-derived DA neurons with the A53T SNCA mutation.
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