Author

H. Alamir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Wuelfing· 2 shared D. J. Morgan· 2 shared G. L. Edmunds· 2 shared A. Alsubaiti· 1 shared A. M. Gallimore· 1 shared C. J. Holland· 1 shared C. W. C. Wong· 1 shared C. W. L. Wong· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

C. Wuelfing

Mutual co-authors in cluster

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2 papers

Recent·Most cited

TIM3 is a context-dependent co-regulator of cytotoxic T cell function

H. Alamir, C. W. C. Wong, A. Alsubaiti, G. L. Edmunds, T. Grant, S. Alsulaimani, J. Boyd, C. J. Holland, D. J. Morgan, A. M. Gallimore, C. Wuelfing

This study shows TIM3 inhibits spheroid-suppressed CTL but not active CTL, and its function depends on the context of T cell activation and ligand expression.

bioRxiv · Aug 3, 2023Immunology

The adenosine 2a receptor and TIM3 directly inhibit killing of tumor cells by cytotoxic T lymphocytes through interference with cytoskeletal polarization

G. L. Edmunds, C. W. L. Wong, R. Ambler, E. Milodowski, H. Alamir, S. J. Cross, G. Galea, C. Wuelfing, D. J. Morgan

This study identifies adenosine 2a receptor and TIM3 as inhibitors of CTL-mediated tumor cell killing by interfering with cytoskeletal polarization and infiltration.

bioRxiv · May 20, 2021Immunology