ImmunologybioRxiv
The adenosine 2a receptor and TIM3 directly inhibit killing of tumor cells by cytotoxic T lymphocytes through interference with cytoskeletal polarization
G. L. Edmunds, C. W. L. Wong, R. Ambler…·D. J. Morgan
This study identifies adenosine 2a receptor and TIM3 as inhibitors of CTL-mediated tumor cell killing by interfering with cytoskeletal polarization and infiltration.
DOI 10.1038/s42003-021-02972-8