J. Boyd

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

This paper shows that varying hyaluronic acid molecular weight in collagen-HA hydrogels can direct macrophage polarization, but chemical crosslinking of HA prevents this effect.

TIM3 is a context-dependent co-regulator of cytotoxic T cell function

This study shows TIM3 inhibits spheroid-suppressed CTL but not active CTL, and its function depends on the context of T cell activation and ligand expression.

The Single-Cell Transcriptome Program of Nodule Development Cellular Lineages in Medicago truncatula

The paper characterizes single-cell transcriptomes during Medicago truncatula nodule development, revealing dynamic changes in auxin and cytokinin signaling pathways across cell lineages.

A Transducing Bacteriophage Infecting Staphylococcus epidermidis Contributes to the Expansion of aNovel Siphovirus Genus and Implies Genus is Inappropriate for Phage Therapy

The paper reports a novel siphovirus phage infecting Staphylococcus epidermidis that can transduce antibiotic resistance, suggesting the genus is unsuitable for phage therapy.

SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19

This study shows SARS-CoV-2 infects human adipose tissue, causing inflammation linked to severe COVID-19 outcomes in obese individuals.

Propionic acid promotes the virulent phenotype of Crohns disease-associated adherent-invasive Escherichia coli

This study shows that propionic acid exposure increases virulence in adherent-invasive Escherichia coli, leading to higher persistence in mice and altered gene expression.

Divergent methyl-coenzyme M reductase genes in a deep-subseafloor Archaeoglobi

This study identifies a new Archaeoglobi lineage with divergent MCR genes, expanding the known evolutionary history of methane-generating archaea.