ImmunologybioRxiv
LUBAC is required for RIG-I sensing of RNA viruses
H. C. Teague, C. Lefevre, E. Rieser…·B. J. Ferguson
This study shows that LUBAC components HOIP and HOIL-1 are required for RIG-I sensing of RNA viruses, while SHARPIN is not, highlighting LUBAC's role in antiviral immunity.
DOI 10.1038/s41418-023-01233-x