The crosstalk between DNA-PK and cGAS drives tumor immunogenicity
C. Taffoni, J. Marines, H. Chamma, M. Saccas, A. Bouzid, S. Guha, A.-L. Chaves Valadao, K. Polak, M. Del Rio, C. Gongora, D. Pineau, J.-P. Hugnot, K. Kissa, L. Fontenille, F. P. Blanchet, , N. Laguette
This study shows DNA-PK and cGAS work together to drive inflammation in tumors, affecting immunogenicity and patient outcomes.
bioRxiv · Jun 8, 2022 · PreprintCancer Biology