LC-MS/MS-PRM Quantification of IgG glycoforms using stable isotope labeled IgG1 Fc glycopeptide standard
M. Sanda, Q. Yang, G. Zong, H. Chen, Z. Zheng, H. Dhani, K. Khan, A. Kroemer, L.-X. Wang, R. Goldman
The paper introduces a workflow for quantifying IgG glycoforms using stable isotope labeled standards and LC-MS/MS-PRM, achieving high sensitivity and precision.
bioRxiv · Aug 2, 2022Biochemistry