Author

L.-X. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Zong· 2 shared M. Sanda· 2 shared Q. Yang· 2 shared R. Goldman· 2 shared A. Cook· 1 shared A. Gajewski· 1 shared A. Kroemer· 1 shared B. Nagata· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

G. Zong

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5 papers

Recent·Most cited

Ghost fragment ions in structure and site-specific glycoproteomics analysis

D. Campos, M. A. Y. Girgis, Q. Yang, G. Zong, R. Goldman, L.-X. Wang, M. Sanda

The paper identifies 'Ghost' fragment ions in glycoproteomics that can lead to false positive structure assignments and proposes a minimal intensity threshold to mitigate this issue.

bioRxiv · May 17, 2023Biochemistry

Structure of a fungal 1,3-β-glucan synthase

C.-R. Zhao, Z.-L. You, D.-d. Chen, J. Hang, Z.-B. Wang, L.-X. Wang, P. Zhao, J. Qiao, C.-H. Yun, L. Bai

This study determines the cryo-EM structure of Saccharomyces cerevisiae 1,3-β-glucan synthase Fks1, revealing its catalytic mechanism and the role of disulfide bonds in enzymatic activity.

bioRxiv · Mar 19, 2023Biophysics

LC-MS/MS-PRM Quantification of IgG glycoforms using stable isotope labeled IgG1 Fc glycopeptide standard

M. Sanda, Q. Yang, G. Zong, H. Chen, Z. Zheng, H. Dhani, K. Khan, A. Kroemer, L.-X. Wang, R. Goldman

The paper introduces a workflow for quantifying IgG glycoforms using stable isotope labeled standards and LC-MS/MS-PRM, achieving high sensitivity and precision.

bioRxiv · Aug 2, 2022Biochemistry

An intranasally administrated SARS-CoV-2 beta variant subunit booster vaccine prevents beta variant viral replication in rhesus macaques

Y. Sui, J. Li, H. Andersen, R. Zhang, S. Prabhu, T. Hoang, D. Venzon, A. Cook, R. Brown, E. Teow, J. Velasco, L. Pessaint, I. Moore, L. lagenaur, J. Talton, , J. Berzofsky

An intranasal SARS-CoV-2 beta variant subunit booster vaccine induced protective immunity against beta variant infection in rhesus macaques one year after initial vaccination.

bioRxiv · Oct 19, 2021Immunology

FcRn, but not FcgRs, drives maternal-fetal transplacental transport of human IgGantibodies

S. Borghi, S. Bournazos, N. Thulin, C. Li, A. Gajewski, R. Sherwood, S. Zhang, E. Harris, P. Jagannathan, L.-X. Wang, J. V. Ravetch, T. T. Wang

This study shows that FcRn, not FcγRs, is responsible for maternal-fetal transport of IgG antibodies, suggesting FcRn engineering could improve antibody transfer to the fetus.

bioRxiv · Mar 22, 2020Immunology