Author

H. E. George

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

C. E. Wyant· 1 shared S. Dhakal· 1 shared S. E. Morgan· 1 shared V. Rangachari· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

C. E. Wyant

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1 paper

Recent·Most cited

BiophysicsbioRxivDec 12, 2020

Prion-like C-terminal domain of TDP-43 and α-Synuclein interact synergistically to generate neurotoxic hybrid fibrils

S. Dhakal, C. E. Wyant, H. E. George…·V. Rangachari

This study investigates the synergistic interaction between TDP-43's prion-like domain and α-synuclein, showing they form toxic hybrid fibrils with increased cytotoxicity.

DOI 10.1016/j.jmb.2021.166953

protein structureexperimental assay

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