L. Stella

Rapid assessment of susceptibility of bacteria and erythrocytes to antimicrobial peptides by single-cell impedance cytometry

This paper introduces a rapid single-cell method using impedance cytometry to assess antimicrobial peptides' effects on bacteria and erythrocytes, showing high-frequency impedance phase as a reliable metric for activity and toxicity.

Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting its Protein-Protein Interactions

This study develops peptide-based SHP2 inhibitors that target protein-protein interactions, showing higher affinity for pathogenic variants and efficacy in zebrafish embryos.

Inoculum effect of antimicrobial peptides

This study systematically characterizes the inoculum effect for antimicrobial peptides, showing that their activity varies with initial cell density, challenging current screening methods.

Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase

This study uses molecular dynamics simulations to analyze the structural determinants of phosphopeptide binding to the N-SH2 domain of SHP2, identifying key residues and interactions that influence binding affinity and specificity.