Pharmacology & ToxicologybioRxivPreprint
Improving the solubility of pseudo-hydrophobic Alzheimer's Disease medicinal chemicals through co-crystal formulation
A. Tse, I. Janilkarn-Urena, J. Lin…·P. M. Seidler
This study shows that forming salts of dihydromyricetin (DHM) improves its solubility and inhibitory activity against Alzheimer's disease tau, suggesting potential for medicinal chemistry applications.
DOI 10.1101/2023.04.25.538327