BiochemistrybioRxiv
Conversion of methionine biosynthesis in E. coli from trans- to direct-sulfurylation enhances extracellular methionine levels
N. Gruzdev, Y. Hacham, H. Haviv…·I. Yadid
This paper enhances L-methionine production in E. coli by replacing the trans-sulfurylation pathway with direct-sulfurylation, achieving up to 160-fold higher extracellular methionine levels.
DOI 10.1186/s12934-023-02150-x