Under-Oil Autonomously Regulated Oxygen Microenvironments: A Goldilocks Principle-Based Approach For Microscale Cell Culture
C. Li, M. Humayun, G. M. Walker, K. Y. Park, B. Connors, J. Feng, M. C. Pellitteri Hahn, C. O. Scarlett, J. Li, Y. Feng, R. L. Clark, H. Hefti, J. Schrope, O. S. Venturelli, D. J. Beebe
This paper introduces a method to create autonomously regulated oxygen microenvironments in microscale cell cultures using an oil overlay, validated with simulations and experiments across multiple cell types.
Advanced Science · Feb 4, 2022Peer-reviewedBioengineering