A spatial stochastic model reveals the role of supercoiling in transcription regulation
Y. Geng, C. H. Bohrer, N. Yehya, H. Hendrix, L. Shachaf, J. Liu, J. Xiao, E. Roberts
This paper develops a spatial stochastic model to show how supercoiling affects transcription regulation in E. coli by enabling communication between RNA polymerase molecules and coordinating gene expression.
bioRxiv · Dec 29, 2021Biophysics