Sex differences in NK cells mediated by the X-linked epigenetic regulator UTX
M. I. Cheng, L. Riggan, J. H. Li, R. Y. Tafti, S. Chin, F. Ma, M. Pellegrini, H. Hrncir, A. P. Arnold, T. E. O'Sullivan, M. A. Su
This study identifies UTX as a key X-linked epigenetic regulator causing sex differences in NK cell function, with males showing reduced IFN-γ production despite higher numbers.
bioRxiv · Apr 21, 2022 · PreprintImmunology