Author

H. Lenthall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. G. Stewart· 2 shared A. Kelleher· 2 shared D. B. Langley· 2 shared D. Christ· 2 shared J. Jackson· 2 shared J. Y. Henry· 2 shared M. Sobti· 2 shared O. Mazigi· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. G. Stewart

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2 papers

Recent·Most cited

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

R. Rouet, J. Y. Henry, M. D. Johansen, M. Sobti, H. Balachandran, D. B. Langley, G. Walker, H. Lenthall, J. Jackson, S. Ubiparipovic, O. Mazigi, P. Schofield, D. L. Burnett, S. H. J. Brown, M. Martinello, , D. Christ

This paper isolates broadly neutralizing SARS-CoV-2 antibodies from convalescent patients and shows they neutralize emerging variants more effectively than existing monoclonal antibodies.

bioRxiv · Oct 19, 2022Immunology

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

R. Rouet, O. Mazigi, G. J. Walker, D. B. Langley, M. Sobti, P. Schofield, H. Lenthall, J. Jackson, S. Ubiparipovic, J. Y. Henry, A. Abayasingam, D. Burnett, A. Kelleher, R. Brink, R. A. Bull, , D. Christ

This paper explores antibody maturation strategies to enhance the neutralization of SARS-CoV-2 using SARS-CoV-1 antibodies, finding that some variants show potent neutralization with IC50 of 160 ng/ml.

bioRxiv · Dec 14, 2020Immunology