A. G. Stewart

This paper isolates broadly neutralizing SARS-CoV-2 antibodies from convalescent patients and shows they neutralize emerging variants more effectively than existing monoclonal antibodies.

This study determines the crystal structures of GIGYF1/2 GYF domains interacting with TNRC6 proteins, revealing how they bridge 4EHP to miRNA targets for translational repression.

The paper reports the cryo-EM structure of a glutamate transporter homologue, revealing a conserved chloride channel with two hydrophobic gates that facilitates dual-function transport.

This study determines the structure of the binding dwell state of F1-ATPase and provides a structural basis for the entire rotary catalysis cycle.

This paper explores antibody maturation strategies to enhance the neutralization of SARS-CoV-2 using SARS-CoV-1 antibodies, finding that some variants show potent neutralization with IC50 of 160 ng/ml.

This study presents cryo-EM structures of E. coli ATP synthase showing how the ε subunit modulates central stalk flexibility to regulate enzyme activity.

The paper identifies and characterizes third-generation cephalosporin-resistant Enterobacteriaceae isolates using PCR and whole-genome sequencing, revealing common ESBLs and rare carbapenemases.

The paper reports the structures of TF55β chaperonin from Sulfolobus solfataricus in open and filamentous states using cryo-EM, revealing conformational changes related to nucleotide binding and filament formation.

The paper presents high-resolution cryo-EM structures of E. coli F1Fo ATP synthase and describes a rotational sub-step of the Fo motor that explains how the F1 and Fo motors are coupled with minimal energy loss.