Author

H. Lewis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. C.-Y. Chang· 1 shared A. H. Yen· 1 shared A. J. Iacano· 1 shared A. K. Denisin· 1 shared A. S. Vander Roest· 1 shared B. B. Goldberg· 1 shared B. Pruitt· 1 shared B. SRINIVASAN· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

A. C.-Y. Chang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nationwide Inclusive Facilitator Training: Mindsets, Practices and Growth

D. Codding, A. H. Yen, H. Lewis, V. Johnson-Ojeda, R. F. Frey, S. C. Hokanson, B. B. Goldberg

This paper evaluates a national facilitator training program for inclusive teaching, finding increased confidence and alignment with DEI practices among participants.

bioRxiv · Jan 8, 2024Scientific Communication & Education

Accelerating the Validation of Endogenous On-Target Engagement and In-cellulo Kinetic Assessment for Covalent Inhibitors of KRASG12C in Early Drug Discovery

V. Kantae, R. Polanski, H. Lewis, D. Barratt, B. SRINIVASAN

This paper develops a high-throughput targeted proteomics workflow using UPLC-MRM to assess on-target engagement of covalent inhibitors in cells, demonstrating its application with KRASG12C.

bioRxiv · Feb 17, 2022Biochemistry

Insights into single hiPSC-derived cardiomyocyte phenotypes and maturation using ConTraX, an efficient pipeline for tracking contractile dynamics

G. Pardon, H. Lewis, A. S. Vander Roest, E. A. Castillo, R. E. Wilson, A. K. Denisin, C. A. Blair, F. Birnbaum, C. Holbrook, K. Koleckar, A. C.-Y. Chang, H. M. Blau, B. Pruitt

The paper develops ConTraX, a pipeline to track contractile dynamics in single hiPSC-CMs, revealing maturation patterns through high-dimensional clustering.

bioRxiv · Mar 18, 2021 · PreprintBioengineering

Miltefosine increases macrophage cholesterol release and inhibits NLRP3-inflammasome assembly and IL-1β release.

A. J. Iacano, H. Lewis, J. E. Hazen, H. Andro, J. D. Smith, K. Gulshan

This paper shows that Miltefosine increases macrophage cholesterol release and inhibits NLRP3 inflammasome assembly and IL-1β release.

bioRxiv · Jun 22, 2019Cell Biology