Author

K. Gulshan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 2 Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 5 Research Focus:cancer & tumor microenvironment· 4 Research Focus:cell signaling & trafficking· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. Opoku· 5 shared C. A. Traughber· 4 shared J. D. Smith· 4 shared A. J. Iacano· 3 shared G. Brubaker· 3 shared J. Smith· 3 shared K. Neupane· 2 shared M. Khan· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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5 shared papersCell Biology

E. Opoku

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice.

C. A. Traughber, K. Timinski, A. Prince, N. Bhandari, K. Neupane, M. R. Khan, E. Opoku, E. Opoku, G. Brubaker, K. Nageshwar, E. G. Ertugral, P. Naggareddy, C. R. Kothapalli, J. Smith, K. Gulshan

bioRxiv · Oct 17, 2023Cell Biology

Miltefosine attenuates inflammation, reduces atherosclerosis, and alters gut microbiota in hyperlipidemic mice.

C. A. Traughber, A. J. Iacano, M. R. Khan, K. Nepane, E. Opoku, T. Nunn, N. Sangwan, S. L. Hazen, J. Smith, K. Gulshan

bioRxiv · Aug 22, 2022 · PreprintCell Biology

Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice.

c. Traughber, G. deshpande, k. neupane, M. Khan, M. R. McMullen, S. Swaidani, E. Opoku, S. Muppals, J. Smith, L. Nagy, K. Gulshan

This study shows that GsdmD in myeloid cells promotes lung cancer metastasis in mice by enhancing inflammasome activity and IL-1β release.

bioRxiv · Aug 22, 2022Cancer Biology

Gasdermin D mediates inflammation-induced defects in reverse cholesterol transport and promotes atherosclerosis.

E. Opoku, C. A. Traughber, D. Zhang, A. J. Iacano, M. Khan, J. Han, J. D. Smith, K. Gulshan

bioRxiv · Apr 16, 2021Pathology

SR-B1 uptake of HDL promotes prostate cancer proliferation and tumor progression

C. A. Traughber, E. Opoku, G. Brubaker, J. Major, H. Lu, S. W. Lorkowski, C. Neumann, A. Hardaway, Y.-M. Chung, K. Gulshan, N. Sharifi, J. M. Brown, J. D. Smith

bioRxiv · Feb 24, 2020 · PreprintCancer Biology

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

G. Brubaker, S. W. Lorkowski, K. Gulshan, S. L. Hazen, V. Gogonea, J. D. Smith

This study shows that the first eight residues of apoA1 lower the barrier to helical bundle unfolding, enabling lipidation, while C-terminus deletion prevents this process.

bioRxiv · Aug 20, 2019Biochemistry

Miltefosine increases macrophage cholesterol release and inhibits NLRP3-inflammasome assembly and IL-1β release.

A. J. Iacano, H. Lewis, J. E. Hazen, H. Andro, J. D. Smith, K. Gulshan

This paper shows that Miltefosine increases macrophage cholesterol release and inhibits NLRP3 inflammasome assembly and IL-1β release.

bioRxiv · Jun 22, 2019Cell Biology