Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level
A. Yamaguchi, N. Maeshige, H. Noguchi, J. Yan, X. Ma, M. Uemura, D. Su, H. Kondo, K. Sarosiek, H. Fujino
This study shows high-intensity ultrasound increases anti-inflammatory EV secretion from skeletal myotubes by raising intracellular calcium levels, which reduces pro-inflammatory gene expression in macrophages.
bioRxiv · Jun 14, 2023Immunology