MicrobiologybioRxivPreprint
pH-dependent spontaneous hydrolysis rather than gut bacterial metabolism reduces levels of the ADHD treatment, Methylphenidate
J. Aresti, W. Maho, R. R. Pereira…·S. El Aidy
This study shows that pH-dependent spontaneous hydrolysis, not gut bacterial metabolism, reduces methylphenidate levels, affecting its bioavailability.
DOI 10.1101/2020.07.06.189191