Cancer BiologybioRxivPreprint
Phosphatase activity is dispensable for PRL-3-mediated oncogenesis and tumor progression
Jeffery T. Jolly, Majd A. Al‐Hamaly, Caroline N. Smith…·Jessica S. Blackburn
This study shows PRL-3 promotes cancer without needing its phosphatase activity, using zebrafish and cell line models, and suggests targeting its protein interactions as a therapy.
DOI 10.1101/2025.05.14.654016