BiochemistrybioRxiv
HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV
D. H. Hock, B. Reljic, C.-S. Ang…·D. A. Stroud
This study shows HIGD2A is essential for assembling the COX3 module of human mitochondrial complex IV, leading to defects in complex IV activity and intermediate accumulation.
DOI 10.1074/mcp.ra120.002076