Author

M. T. Ryan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. A. Stroud· 5 shared B. Reljic· 3 shared A. J. Sharpe· 2 shared D. R. Thorburn· 2 shared L. Muellner-Wong· 2 shared A. E. Frazier· 1 shared A. G. Compton· 1 shared A. J. Anderson· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersBiochemistry

D. A. Stroud

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Caveolae respond to acute oxidative stress through membrane lipid peroxidation, cytosolic release of CAVIN1, and downstream regulation of NRF2

Y. Wu, Y.-W. Lim, D. A. Stroud, N. Martel, T. E. Hall, H. Lo, C. Ferguson, M. T. Ryan, K.-A. McMahon, R. G. Parton

This study shows that caveolae regulate oxidative stress response by lipid peroxidation, CAVIN1 release, and NRF2 interaction, affecting cell death and regeneration.

bioRxiv · Jun 9, 2021 · PreprintCell Biology

Optic Atrophy-associated TMEM126A is an assembly factor for the ND4-module of Mitochondrial Complex I

L. Formosa, B. Reljic, A. J. Sharpe, L. Muellner-Wong, D. A. Stroud, M. T. Ryan

This study identifies TMEM126A as a critical assembly factor for the ND4-module of mitochondrial complex I, distinct from its paralogue TMEM126B, which assembles the ND2-module.

bioRxiv · Sep 18, 2020Biochemistry

HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV

D. H. Hock, B. Reljic, C.-S. Ang, H. S. Mountford, A. G. Compton, M. T. Ryan, D. R. Thorburn, D. A. Stroud

This study shows HIGD2A is essential for assembling the COX3 module of human mitochondrial complex IV, leading to defects in complex IV activity and intermediate accumulation.

bioRxiv · Dec 19, 2019Biochemistry

Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly (MCIA) Complex Factors in the Biogenesis of Complex I

L. E. Formosa, L. Muellner-Wong, B. Reljic, A. J. Sharpe, T. H. Beilharz, M. Lazarou, D. A. Stroud, M. T. Ryan

The paper identifies TMEM186 and COA1 as new components of the MCIA complex and elucidates their roles in complex I assembly.

bioRxiv · Oct 17, 2019Biochemistry

Neuronal-specific function of hTim8a in Complex IV assembly provides insight into the molecular mechanism underlying Mohr-Tranebjaerg syndrome

Y. Kang, A. J. Anderson, D. P. De Souza, C. S. Palmer, K. M. Fujihara, T. Stait, A. E. Frazier, N. J. Clemons, D. Tull, D. R. Thorburn, M. J. McConville, M. T. Ryan, D. A. Stroud, D. Stojanovski

This study identifies hTim8a's role in neuronal Complex IV assembly and shows how its loss causes oxidative stress and apoptosis, contributing to Mohr-Tranebjaerg syndrome.

bioRxiv · Aug 5, 2019 · PreprintCell Biology