Encephalitic alphaviruses exploit caveolae-mediated transcytosis at the blood-brain barrier for CNS entry
R. S. Klein, H. Salimi, M. D. Cain, X. Jiang, R. Roth, W. Beatty, C. Sun, W. B. Klimstra, J. S. Hou
This study shows alphaviruses use caveolae-mediated transcytosis across the blood-brain barrier to enter the CNS, and IFN restricts this process.
bioRxiv · Oct 16, 2019 · PreprintMicrobiology