Author

H. Shukla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Griffiths· 1 shared A. Khan· 1 shared A. N. Honko· 1 shared A. Polley· 1 shared A. Viswanathan· 1 shared A. Zachariah· 1 shared B. C. Heimbach· 1 shared C. Nicolescu· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Griffiths

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Author profile →

2 papers

Recent·Most cited

Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers

A. Khan, K. Patel, H. Shukla, A. Viswanathan, T. van der Valk, U. Borthakur, P. Nigam, A. Zachariah, Y. Jhala, M. Kardos, U. Ramakrishnan

This study uses whole-genome sequencing of Indian tigers to show that small-isolated populations have higher inbreeding depression and purging of deleterious alleles compared to larger, connected populations.

Proceedings of the National Academy of Sciences · Nov 30, 2021Peer-reviewedEvolutionary Biology

Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody Cocktail

P. A. Nikitin, J. M. DiMuzio, J. P. Dowling, N. B. Patel, J. L. Bingaman-Steele, C. Nicolescu, B. C. Heimbach, N. Henriquez, E. L. Sikorsky, A. Polley, R. J. Howanski, M. Nath, H. Shukla, S. M. Scheaffer, J. P. Finn, , M. K. Robinson

The paper identifies and characterizes an antibody cocktail, IMM-BCP-01, that neutralizes SARS-CoV-2 variants in vitro and inhibits infection in vivo through Spike Trimer dissociation and effector responses.

bioRxiv · Oct 18, 2021 · PreprintImmunology