Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV
V. A. Matveev, E. Z. Mihelic, E. Benko, P. Budylowski, S. Grocott, T. Lee, C. S. Korosec, K. Colwill, H. Stephenson, R. Law, L. A. Ward, S. Sheikh-Mohamed, G. Mailhot, M. Delgado-Brand, A. Pasculescu, , M. Ostrowski
This study evaluates the immunogenicity of COVID-19 vaccines in older people with HIV and their impact on HIV reservoirs, finding that three doses are needed for optimal neutralizing responses but vaccines may increase HIV reservoirs in those with persistent viremia.
bioRxiv · Jun 14, 2023Immunology