Author

H. V. Jain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

H. Byrne· 1 shared I. C. Sorribes· 1 shared I. Sorribes· 1 shared M. N. Moore· 1 shared S. K. Handelman· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperCancer Biology

H. Byrne

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2 papers

Recent·Most cited

Cancer BiologybioRxivOct 5, 2019

Mitigating Temozolomide Resistance in Glioblastoma via DNA Damage-Repair Inhibition

I. C. Sorribes, S. K. Handelman, H. V. Jain

This study develops a mechanistic model to identify optimal combination therapies for overcoming temozolomide resistance in glioblastoma by targeting DNA repair enzymes.

DOI 10.1098/rsif.2019.0722

humanmechanistic / dynamical model

𝕏 PostBluesky

Cancer BiologybioRxivNov 29, 2018

A Biomechanical Model of Tumor-induced Intracranial Pressure and Edema in Brain Tissue

I. Sorribes, H. Byrne, M. N. Moore, H. V. Jain

This paper develops a biomechanical model to simulate tumor-induced intracranial pressure and edema, linking ICP dynamics to tumor grade and clinical symptoms.

DOI 10.1016/j.bpj.2019.02.030

humanbiophysical modeling

𝕏 PostBluesky