BiochemistrybioRxiv
ABC-transporter CFTR folds with high fidelity through a modular, stepwise pathway
J. Im, T. Hillenaar, H. Y. Yeoh…·I. Braakman
This study reveals the stepwise folding pathway of CFTR, showing two distinct stages of domain folding and assembly, with implications for understanding protein misfolding diseases.
DOI 10.1007/s00018-022-04671-x