Induced Arp2/3 complex depletion increases FMNL2/3 formin expression and filopodia formation
V. Dimchev, I. Lahmann, S. A. Koestler, F. Kage, G. Dimchev, A. Steffen, T. E. Stradal, F. Vauti, H.-H. Arnold, K. Rottner
This study shows that acute Arp2/3 complex depletion increases FMNL2/3 formin expression and filopodia formation in fibroblasts, despite reduced actin turnover and impaired lamellipodia formation.
bioRxiv · Dec 3, 2020Cell Biology