Author

H.-H. Hu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Organism:Drosophila· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

C.-J. Guo· 3 shared J.-L. Liu· 3 shared X. Zhou· 3 shared B. Yin· 2 shared C.-C. Chang· 2 shared G.-M. Lu· 2 shared J. Zhong· 2 shared T. Zhang· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

C.-J. Guo

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 11, 2022

Structural basis of human PRPS2 filaments

G.-M. Lu, H.-H. Hu, C.-C. Chang…·J.-L. Liu

This study determines the structure of hPRPS2 polymers using cryo-EM, revealing how ADP binding affects polymerization and catalytic activity.

DOI 10.1101/2022.07.11.499506

BiochemistrybioRxivDec 2, 2021

Structural basis of dynamic P5CS filaments

J. Zhong, C.-J. Guo, X. Zhou…·J.-L. Liu

This study determines the structure of Drosophila P5CS filament, revealing how filamentation coordinates GK and GPR domains for catalysis.

DOI 10.7554/elife.76107

Drosophilacryo-EM

Cell BiologybioRxivDec 11, 2019

The proline synthesis enzyme P5CS forms cytoophidia in Drosophila

B. Zhang, O. Y. Tastan, X. Zhou…·J.-L. Liu

The paper identifies P5CS as a CTPS-interacting protein in Drosophila and shows they form cytoophidia, linking two enzymes in pyrimidine and proline biosynthesis.

DOI 10.1016/j.jgg.2020.02.005

Drosophilaexperimental assay