Genetic & Genomic MedicineCancer ResearchPeer-reviewed
Aberrant transcript usage induces homologous recombination deficiency and predicts therapeutic responses
Hyeon Gu Kang, Haeun Hwangbo, Myung Ji Kim…·Jung Kyoon Choi
The paper identifies transcriptional HRD (tHRD) based on aberrant transcript usage as a more accurate predictor of PARP inhibitor and DNA damaging agent responses than genomic HRD tests.
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