ImmunologyVeterinary MicrobiologyPeer-reviewed
ASFV early protein p30 suppresses antiviral type I IFN induction by targeting TRIM21 and RIG-I like receptor signaling adaptor MAVS
J B Zhang, Hanrong Lv, Ding Jin…·Jianzhong Zhu
This study identifies ASFV p30's role in suppressing antiviral type I IFN induction by interacting with TRIM21 and MAVS, disrupting TRIM21-mediated K27 polyubiquitination of MAVS.