NeurosciencebioRxivPreprint
Synaptic changes contribute to persistent extra-motor behaviour deficits in the rNLS8 TDP-43 mouse model of amyotrophic lateral sclerosis
Wei Luan, Rebecca San Gil, Lidia Madrid San Martin…·Adam K. Walker
This study identifies persistent extra-motor behavioural deficits in rNLS8 TDP-43 mice, linked to synaptic gene expression and splicing changes that persist even after motor recovery.
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