Cell BiologybioRxivPreprint
Mechanically induced pre-mitotic nuclear deformations promote nuclear rupture through lamin B1 depletion
Myron N.F. Hensgens, Haochun Sun, Dr Boyd Peters…·Hylkje J. Geertsema
The paper shows that microtubule-dependent nuclear invaginations cause lamin B1 depletion and nuclear rupture through mechanical stress, aiding mitotic entry.
DOI 10.64898/2026.07.17.739104