BiophysicsiSciencePeer-reviewed
Mapping Structural Distribution and Gating-Property Impacts of Disease-Associated Missense Mutations in Voltage-Gated Sodium Channels
Amin Akbari Ahangar, Eslam Elhanafy, Hayden Blanton, Jing Li
This study maps disease-associated missense mutations in voltage-gated sodium channels and shows that their effects on channel function are more nuanced than traditional gain-of-function or loss-of-function classifications.
10 citations