Cancer BiologybioRxivPreprint
Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium
Oscar Pellón-Cárdenas, P Rout, S Hassan…·MP Verzi
The paper shows Pdgfra+ fibroblasts reprogram during WNT-driven oncogenesis to promote a regenerative state in the epithelium, facilitating tumor formation.