BiochemistrybioRxivPreprint
HMCES DNA-protein cross-links promote template slippage during DNA replication
He Xu, Yixin Clem Xu, Yuge Chai…·Daniel R. Semlow
This study shows HMCES-DPC formation increases DNA template flexibility, enabling slippage and mutagenic bypass of AP sites during replication.
DOI 10.64898/2026.08.14.744967