NeurosciencebioRxivPreprint
Endothelial expression of human APP leads to cerebral amyloid angiopathy in mice
Yuriko Tachida, Saori Miura, Rie Imamaki…·Shinobu Kitazume
This study shows that expressing human APP in endothelial cells of mice leads to cerebral amyloid angiopathy, highlighting the role of both neuronal and endothelial APP in vascular Aβ deposition.
1 citation