Author

Hilary A. Edgington

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

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Armande Ang Houle· 1 shared Aurelien Chateigner· 1 shared Fabien C. Lamaze· 1 shared Marie-Julie Fave· 1 shared PCAWG3· 1 shared Philip Awadalla· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperCancer Biology

Armande Ang Houle

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 11, 2017

Motif Disruption Domains Lead To Cancer Gene Expression Rewiring

Fabien C. Lamaze, Aurelien Chateigner, Hilary A. Edgington…·Philip Awadalla

The paper identifies and characterizes motif disruption domains (MDDs) across 40 cancer types, showing their role in gene expression dysregulation through disruption of transcription factor binding sites.

DOI 10.1101/126359

humanwhole-genome sequencing

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