Molecular BiologybioRxivPreprint
Differential clearance rate of proteins encoded on a self-amplifying mRNA vaccine in muscle and lymph nodes
Reo Kanechi, Tatsuya Shishido, Mana Tachikawa…·Marito Araki
This study investigates the differential clearance rates of spike protein and replicase components from a self-amplifying mRNA vaccine in muscle and lymph nodes, linking prolonged expression in lymph nodes to sustained antibody levels.
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